Sickle cell anemia mainly affects people in Africa, the Mediterranean, the Middle East, Asia and Indian descent. There is also a growing segment of the population in Latin America, in particular, the Caribbean, Central and South American descent. In the U.S. one in every 400 men have this disease. The most common form of sickle cell disease is sickle cell anemia. In our companion article "Understanding sickle cell anemia, we cover a lot of material onthe causes and symptoms of this disease. The following paragraph is a very brief overview.
All types of sickle cell disease are caused by a genetic change in the hemoglobin of red blood cells. Hemoglobin is the oxygen-carrying protein in red blood cells. normal red blood cells are oval and flexible. Red blood cells in sickle cell disease have a tendency to transform into rod-shaped structures that resemble the curved blade of a scythe, sickle, hence the termCell Sickle cells have a shorter than normal red blood cells. This leads to chronic anemia and reduced oxygen to body tissues. In addition, sickle cells are less flexible than normal red blood cells. This presents a problem because they can be trapped in small blood vessels prevents blood flow to body tissues. This compromise in the supply of oxygen to the tissues leading to pain and possible tissue damage and associated organs.
RecentlyThe research highlights the importance of nitric oxide!
Researchers at Duke University and Howard Hughes Medical Institute recently discovered a key to the cause of pain in sickle cell disease. Their results were reported in the January 31, 2005. Proceedings of the National Academy of Sciences. His research showed that when normal red blood through the arteries, a move signaling molecule that indicates the artery walls to expand the space. The signal molecule isNitric oxide. Nitric oxide causes the smooth muscle cells to relax in the vessel wall, which opens the receiver so that the cells through.
distorted for those with sickle cell anemia when red blood cells are sickle cell disease in the form, researchers at Duke University have discovered, not to expand the walls of the arteries. This form of sickle-cell distorted by the fact that they tend to cluster together to block blood flow through these small landArteries and capillaries. The researchers found that the Duke pulses of blood, the walls of the arteries, not how to expand the normal red blood cells.
Their research also noted that the level of nitric oxide deficiency directly correlated with the severity of symptoms. This means that nitric oxide is greater than the pain produced. This / HHMI Duke study found that when nitric oxide is to help people with sickle cell anemia, their symptoms were administered. One ofConclusions of this study is that abnormal processing of nitric oxide could be the cause of the limitations of sickle cell anemia blood flow. In addition to the Duke / HHMI study found many other studies that administration of nitric oxide to help people with sickle cell disease symptoms.
awarded the 1998 Nobel Prize in medicine went to researchers in nitric oxide. Part of what came out of their research was that the primary way for the production of nitric oxide in the body came from aessential amino acid called L-arginine. L-arginine is considered an essential amino acid, because your body can not produce, should result in your body through diet. L-Arginine is in foods like milk, cheese, yoghurt, meat and other proteins.
leading researchers in the world of L-arginine is Dr. Ann de Wees Allen. Dr. Allen has over 20 years of experience with L-arginine and their research has a number of breakthroughs, the remarkable properties of LED-CenterL-arginine. In fact, L-arginine was a major developed neutraceuticals ever tested and is known by scientists as the miracle molecule. Columbia University refers to L-arginine as a "miracle cure" for the cardiovascular system.
To be effective and safe, L-arginine must use a method of low glycemic. Through much research and development, Dr. Allen determined that a molecule of L-arginine linked to a glycoside Kiwi (Kiwi system) creates theFormulation that L-arginine may overcome barriers to enable correct and verbally, without rejection palate to be taken. Dr. Allen has made a product called patent granted ProArgi-9 6608109 # With this patent, the FDA and FTC to make Dr. Allen to 15 credits legal ProArgi-9, and the legal right # 14 is "helping to produce oxide nitric acid. "
Two leading researchers are now aware of Dr. Allen's work and products. Dr. Clair Francome (former head of the MedicalGenetics Branch, National Institutes of Medicine, National Genome Research Institute for Human Genetics and head of the Laboratory of Genetics at the National Institute on Aging), and Dr. Randall Maxey (famous American cardiologist and president of the National Medical Association Research Foundation for Ethnic approached diseases), Dr. Allen on their patented for the supply of L-arginine and its ability to produce nitric oxide safe and effective in humans. Because oftheir experience and research in genetics, were aware of another common genetic polymorphism of African-American community. Many African-Americans make too much of an enzyme called arginase. In the blood, destroying Arginase L-arginine, so that is no longer for the production of nitric oxide available.
With the help of Dr. Clair Francome, and Dr. Randall Maxey Dr. Allen was able to genetically modify a low-glycemic delivery specifications for L-arginineDesigned for the African American community. This product is called encoding. It will help provide the body with a high level and quality of L-arginine in a proper production of nitric oxide can with health benefits that can be derived nitric oxide can be achieved.
14 steps to help with sickle cell anemia!
Understanding the past and most current research will contribute to an action plan for those suffering from sickle cell anemia to help chart. Rememberthat these measures are intended for informational purposes and is not a substitute for professional medical advice, examination, diagnosis or treatment. Always consult a doctor or other qualified health professional if you have any questions regarding this or any medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read this article. If you think you can medical emergency, always call a doctoror 911 immediately.
Step 1 - adequate hydration is estimated that 75% of Americans have mild, chronic dehydration. This makes the blood flow so always the right amount of water on a daily basis is influenced by the critics. Must be pure water. Pop, coffee, Diet Coke, alcohol or other beverages are not manipulated. Your body needs 2-3 liters of water daily to replace. As a general rule that for every 15 pounds of weight, you need 8 ounces (1 cup) of water.
Step 2 - Hot Date:Cold reduces blood flow because capillaries close. If you live in a cold environment, then take extra precautions to keep your extremities, especially hands and feet to keep protected.
Step 3 - Avoid high altitude: geographical locations with the share should be avoided due to the reduction of oxygen in the atmosphere.
Step 4 - Exercise of intensive training should be avoided, but mild to moderate aerobic exercise can be an advantage. Exercise improves circulation and mayproduce collateral capillary beds, which may provide alternative pathways to the aid of arterial blood flow, if a route is blocked. Before starting an exercise program, you should always consult your doctor.
Step 5 - L-Arginine: The body uses L-arginine to nitric oxide, which is responsible for the proper functioning of the cardiovascular system, particularly in controlling the elasticity of arterial walls to create. Now, before you go and startsupplements of L-arginine must be aware of the dark side of this amino acid. L-arginine taken in its pure form tastes horrible and just go in the stomach, intestine and then move the intestine, to negate most of its benefits. There is only one way to supplement L-arginine is safe and effective, and this is the form of powder with a specific pilot glycoside. By itself, L-arginine have some serious side effects, such as increasing free radical damage to the brain,Activation of herpes simplex virus and reduced sperm motility. Therefore, L-arginine is also called "two-edged sword." Since L-arginine is an amino acid is one blind pilots must be attached to direct it towards the right direction in the area of the body where it will have an impact. These drivers have a low glycemic method.
Step 6 - Organic Germanium: Germanium Organic synthesized for the first time 20 years ago. There is a trace mineral that helps support the immune system. Its many positiveAttributes include accumulation of oxygen free radicals and detoxification of heavy metals. Organic Germanium is also known to force a donor and aid in increasing strength, endurance, energy, heart and muscle tone. Toxicological studies have documented their rapid absorption and excretion from the body. But as a precautionary measure, you should discuss with your doctor and pharmacist to discuss the two especially when you are on any kind of drug.
Step 7 - Rest is important foradequate rest, since stress can affect your overall health and wellbeing, and lower the immune system.
Step 8 - Support the immune system: There is so much you could say in this area. Increase consumption of fruits and vegetables rich in antioxidants is an important first step. The daily consumption of 500 mg of vitamin C could help both the immune system and liver function.
Step 9 - Support to the liver: Again, there is much thatsay in this area. sufficient quantities of green leafy vegetables with water to the right are both of the early successes to help the liver. Less than 500 mg of vitamin C helps to increase the synthesis of glutathione, an important component in the liver is detoxification.
Step 10 - Avoid people with colds and flu: do not try to be in situations that may occur infection site. This may need to use a mask at times when your work or school environment threatDisease issues.
Item 11 - Vaccinations: Stay updated with proper vaccinations. Work with your doctor for a calendar so that all the right steps are taken to stay on top in this field.
Step 12 - Folic acid: Folic acid is a necessary component for the production of red blood cells. The recommended daily dose for adults is 400 micrograms and 600 micrograms during pregnancy. If you record a lot, then you thinkmust talk with both your doctor and pharmacist.
Step 13 - Support groups: due to emotional problems of this disease always helps to find a support group to share frustrations, challenges, hopes and successes.
Step 14 - Family Planning: Because of the genetic nature of sickle cell disease, it is always useful to see the options with a doctor expert in genetic counseling is discussed.
Because of the genetic nature of sickle cell disease, isno pill to cure it. This can leave individuals and family members powerless in their fight against the symptoms of this disease. Discuss these 14 steps with a qualified physician to develop an action plan to help empower you have better control of sickle cell disease.
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